It is crucial for the success of tuberculosis therapy that all medication is taken daily and for the entire recommended period. As the therapy is lengthy and can cause side effects, this is a major challenge for patients. If there are difficulties in taking the medication regularly or correctly, support can be organized by the treating doctors or the health department. This is known as directly observed therapy or DOT. A nursing service, staff from the health authority or even family members can then provide the medication and monitor the daily intake.

DOT is usually carried out at home, but can also take place in health offices or other facilities. DOT aims to support patients while ensuring that all medication is taken. In addition, direct observation helps to recognize side effects of medication at an early stage. Questions about treatment can also be answered immediately.